The house is of the type called bahay na bato but a more airy version, literally "house of stone", however, reflecting American colonial influences, the lower storey is not constructed of stone but of concrete. The foundation posts are made out of trunks of  the  balayong  tree,  a  local  hardwood;   the floorboards are  of the same material. The house's upper storey is constructed of wood topped with a roof of galvanized iron instead of tile.

The house has a four-meter high ceiling and large windows with ventanillas, smaller windows beneath the large windows with sliding panels that can be opened to admit the wind. The lower storey itself is elevated from ground level by a meter-high crawlspace, allowing  the   wooden  foundations  to  be aired, preventing dampness from rotting the wood.

The first floor, raised from the damp earth is pierced by windows that make the interior brighter than older houses. The first floor is no longer just a storage space but large foyer which leads to rooms and offices. The lower floor connects to the upper story  through  a  grand  staircase.  The  upper  floor  has bedrooms flanking the living room. To the rear is the dining hall and kitchen. The upper story is made of wood with generous  ventanillas
that allow air to circulate throughout the house. The house has been furnished  with  furniture  and  appurtenances  donated  by  various  persons.  Arranged as a lifestyle museum, Balay Negrense is also available for social functions, like wedding receptions.